Because of this, type O- is known as the “universal donor.” The universal plasma donor is type AB. Rh-positive blood can only be donated to people who have the Rh protein, and Rh-negative blood can be donated to both negative and positive. Type B can donate to type B, and AB and type AB can only donate to type AB. Generally speaking, type O can donate to everyone, which means type O, A, B, and AB. People with certain blood types are compatible for blood transfusions and certain others are not. If you have to type A blood, for example, you have type A antigens on your red blood cells and anti-B antibodies in your plasma. Antigens are something that triggers your immune system to produce antibodies against a foreign invader. Whether you have type A, B, AB, or O type is determined by the kind of antigens you have on your red blood cells. Your blood can be either RhD positive (+) if you have the protein, or RhD negative (-) if you do not. In addition, each blood type has an Rh factor, or Rhesus factor, which is a protein found in your red blood cells. There are four main known blood types: A, B, AB, and O. Although this is rare, you can die from the reaction. Your immune system could attack the red blood cells in the donated blood. If you get in a car accident or suffer from some other medical problem that requires you to receive a blood transfusion, the donated blood needs to match your own. It is important to know your blood type as it determines the type of blood you can receive in a blood transfusion.
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